This church has a very simple interior, with three naves separated by columns with Corinthian capitals and a zoomorphic (cows, lions and rams) under a vault intersected with ribs. A portico with small polygonal columns with extremely stylised capitals encircles the old cloister.

This vibrant square in the centre of the old town is dominated by the statue of the Patron Saint of the town who occupies one of the two columns that mark the end of the Appian way. It is bordered on its south side by the ruins of the old amphitheatre. In addition, there is Saint-Mark's church built by the Venetian colony, and the antique Piazzi del Seggio which temporarily harbours a statue of Saint Joseph in paper mach,, the region's traditional material.

By several architects and representative of the Lecce Baroque style of the 16 and 17C. The facade which is sumptuously but not overbearing (the upper part) conceals a long narrow and bright interior, which is similar to the style inaugurated in Florence by Briunellesch. It has a Baroque decor which is extremely finely worked and extremely lavish. In the chapel at the end of the left aisle, there is a lovely high-altar with low-reliefs carved by Francesco Antonio Zimbalo.

Built by Giuseppe Zimbalo between 1659 and 1692, this cathedral has sumptuous portals. Inside, the crypt, rebuilt in the 16C, is held up by 92 columns with zoomorphic capitals.